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Warning! 8 drugs that can cause severe dementia

Ouadie RhabbouronMay 28, 2026

Long-term use, especially of oral corticosteroids, has been linked to an increased risk of dementia. They affect levels of the stress hormone cortisol in the brain.

4. Benzodiazepinek

Alprazolam and diazepam can double the risk of Alzheimer’s disease with long-term use, with about 40 percent of users experiencing neurological symptoms.

5. Amphetamines

Amphetamines used to treat ADHD can lead to memory loss and permanent cognitive impairment if used long-term.

6. First-generation antihistamines

Allergy medications containing diphenhydramine can cause cognitive impairment. Safer alternatives include cetirizine and other newer antihistamines.

7. Tricyclic antidepressants

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